HitPredict

Interactor 1: FAN (Q92636)
Protein FAN (Factor associated with neutral sphingomyelinase activation) (Factor associated with N-SMase activation)
Gene: NSMAF

Interactor 2: GBRL1 (Q9H0R8)
Gamma-aminobutyric acid receptor-associated protein-like 1 (Early estrogen-regulated protein) (GABA(A) receptor-associated protein-like 1) (Glandular epithelial cell protein 1) (GEC-1)
Gene: GABARAPL1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.78	0.60	0.686

Property	Details
Experiments	28514442, 33961781, 20562859
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 917 Hs			1 117
+	Hs
		891255 FAN_HUMAN (1-917): 0: 813: 100.00		GBRL2_HUMAN (1-116): 1.39e-57: 175: 61.21
+	Hs
		306258 FAN_HUMAN (1-917): 0: 813: 100.00		GBRAP_HUMAN (1-116): 2.96e-56: 171: 87.07
+	Hs
		1268697 FAN_HUMAN (1-917): 0: 813: 100.00		MLP3C_HUMAN (5-116): 1.61e-44: 143: 39.47
+	Hs
		1268700 FAN_HUMAN (1-917): 0: 813: 100.00		MLP3A_HUMAN (5-116): 1.09e-44: 142: 34.21
+	Hs
		1268698 FAN_HUMAN (1-917): 0: 813: 100.00		MLP3B_HUMAN (2-116): 1.06e-43: 140: 31.62
+	Hs
		891218 WDFY3_HUMAN (87-893): 7.02e-164: 533: 24.22		GBRL2_HUMAN (1-116): 1.39e-57: 175: 61.21
+	Hs
		1152287 WDFY3_HUMAN (87-893): 7.02e-164: 533: 24.22		Q6IAW1_HUMAN (1-116): 2.96e-56: 171: 87.07
+	Hs
		1224700 WDFY3_HUMAN (87-893): 7.02e-164: 533: 24.22		GBRL1_HUMAN (1-117): 4.54e-56: 171: 100.00
+	Hs
		306231 WDFY3_HUMAN (87-893): 7.02e-164: 533: 24.22		GBRAP_HUMAN (1-116): 2.96e-56: 171: 87.07
+	Hs
		1224697 WDFY3_HUMAN (87-893): 7.02e-164: 533: 24.22		MLP3C_HUMAN (5-116): 1.61e-44: 143: 39.47
+	Hs
		1224703 WDFY3_HUMAN (87-893): 7.02e-164: 533: 24.22		MLP3A_HUMAN (5-116): 1.09e-44: 142: 34.21
+	Hs
		1224698 WDFY3_HUMAN (87-893): 7.02e-164: 533: 24.22		MLP3B_HUMAN (2-116): 1.06e-43: 140: 31.62
+	Mm
		1167198 WDFY3_MOUSE (87-793): 1.99e-155: 509: 24.44		MLP3A_MOUSE (5-116): 1.09e-44: 142: 34.21
+	Hs
		891030 WDR5_HUMAN (743-915): 1.38e-54: 194: 19.89		GBRL2_HUMAN (1-116): 1.39e-57: 175: 61.21
+	Dm
		1370863 Q9VML2_DROME (725-917): 4.02e-24: 112: 14.62		Q9W2S2_DROME (1-116): 1.56e-57: 175: 85.35
+	Hs
		842026 LRBA_HUMAN (539-845): 1.89e-27: 122: 13.46		MLP3B_HUMAN (2-116): 1.06e-43: 140: 31.62
+	Hs
		1122381 WDR81_HUMAN (300-576): 8.71e-22: 104: 30.07		MLP3C_HUMAN (5-116): 1.61e-44: 143: 39.47
+	Hs
		1326179 NLE1_HUMAN (454-574): 1.09e-09: 63.9: 9.52		MLP3B_HUMAN (2-116): 1.06e-43: 140: 31.62