Interactor 1: SORL (Q92673)
Sortilin-related receptor (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (SorLA-1) (Sorting protein-related receptor containing LDLR class A repeats) (SorLA)
Gene: SORL1

Interactor 2: SORT (Q99523)
Sortilin (100 kDa NT receptor) (Glycoprotein 95) (Gp95) (Neurotensin receptor 3) (NT3) (NTR3)
Gene: SORT1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.647

The method score is based on:

Property Details
Experiments 11294867
Identification Methods pull down
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Sortilin-Vps10~Sortilin-Vps10, Sortilin_C~Sortilin-Vps10
Common GO terms GO:0005769 - early endosome
GO:0005789 - endoplasmic reticulum membrane
GO:0005794 - Golgi apparatus
GO:0005886 - plasma membrane
GO:0006622 - protein targeting to lysosome
and 4 others

more...

Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 2214
Hs

1 831
+ Hs
+ Hs
+ Hs
+ Sc

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Last updated: 15 Jul 2024