HitPredict

Interactor 1: SORL (Q92673)
Sortilin-related receptor (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (SorLA-1) (Sorting protein-related receptor containing LDLR class A repeats) (SorLA)
Gene: SORL1

Interactor 2: GGA1 (Q9UJY5)
ADP-ribosylation factor-binding protein GGA1 (Gamma-adaptin-related protein 1) (Golgi-localized, gamma ear-containing, ARF-binding protein 1)
Gene: GGA1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.86 0.60 0.720

The method score is based on:

Property Details
Experiments 17855360, 11821067, 26053850, 30679749, 20015111
Identification Methods affinity chromatography technology, two hybrid, pull down, unspecified method, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005769 - early endosome
GO:0005794 - Golgi apparatus
GO:0005802 - trans-Golgi network
GO:0010008 - endosome membrane
GO:0016020 - membrane
and 3 others

more...
Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 2214
Hs

1 639
+ Hs
+ Mm
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024