HitPredict

Interactor 1: NECT2 (Q92692)
Nectin-2 (Herpes virus entry mediator B) (Herpesvirus entry mediator B) (HveB) (Nectin cell adhesion molecule 2) (Poliovirus receptor-related protein 2) (CD antigen CD112)
Gene: NECTIN2

Interactor 2: TMPSD (Q9BYE2)
Transmembrane protease serine 13 (EC 3.4.21.-) (Membrane-type mosaic serine protease) (Mosaic serine protease)
Gene: TMPRSS13

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Trypsin~V-set
Common GO terms	GO:0005886 - plasma membrane GO:0016020 - membrane
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 538 Hs			1 586
+	Hs
		1269142 NECT2_HUMAN (1-538): 1.67e-89: 287: 100.00		ST14_HUMAN (148-559): 1.53e-112: 357: 28.74
+	Hs
		409542 NECT2_HUMAN (1-538): 1.67e-89: 287: 100.00		HEPS_HUMAN (225-562): 2.23e-104: 322: 35.38
+	Hs
		177812 PVR_HUMAN (25-441): 3.32e-61: 209: 42.72		TMPS2_HUMAN (86-560): 5.15e-131: 394: 32.25
+	Hs
		1198117 NECT2_HUMAN (1-538): 1.67e-89: 287: 100.00		TM11B_HUMAN (281-559): 2.19e-100: 312: 33.21
+	Hs
		545175 PVR_HUMAN (25-441): 3.32e-61: 209: 42.72		TMPS4_HUMAN (192-561): 2.81e-117: 356: 35.49
+	Hs
		177883 PTK7_HUMAN (4-527): 3.59e-35: 142: 14.13		TMPS2_HUMAN (86-560): 5.15e-131: 394: 32.25
+	Hs
		545133 PVR_HUMAN (25-441): 3.32e-61: 209: 42.72		TM11B_HUMAN (281-559): 2.19e-100: 312: 33.21
+	Hs
		1031173 PTK7_HUMAN (4-527): 3.59e-35: 142: 14.13		TMPS4_HUMAN (192-561): 2.81e-117: 356: 35.49
+	Hs
		1294957 LRIG1_HUMAN (153-427): 4.08e-34: 139: 14.14		TMPS4_HUMAN (192-561): 2.81e-117: 356: 35.49
+	Hs
		299592 LRIG2_HUMAN (161-392): 3.45e-32: 133: 16.19		TMPS4_HUMAN (192-561): 2.81e-117: 356: 35.49
+	Hs
		1299539 SIG12_HUMAN (31-354): 8.23e-22: 101: 15.07		TMPS4_HUMAN (192-561): 2.81e-117: 356: 35.49
+	Hs
		1031147 PTK7_HUMAN (4-527): 3.59e-35: 142: 14.13		TM11B_HUMAN (281-559): 2.19e-100: 312: 33.21
+	Hs
		1198133 LRIG1_HUMAN (153-427): 4.08e-34: 139: 14.14		TM11B_HUMAN (281-559): 2.19e-100: 312: 33.21
+	Hs
		299569 LRIG2_HUMAN (161-392): 3.45e-32: 133: 16.19		TM11B_HUMAN (281-559): 2.19e-100: 312: 33.21
+	Hs
		1378220 ROBO1_HUMAN (333-538): 1.79e-18: 91.7: 8.92		TEST_HUMAN (305-566): 1.11e-106: 325: 37.23