Interactor 1: NECT2 (Q92692)
Nectin-2 (Herpes virus entry mediator B) (Herpesvirus entry mediator B) (HveB) (Nectin cell adhesion molecule 2) (Poliovirus receptor-related protein 2) (CD antigen CD112)
Gene: NECTIN2

Interactor 2: NECT3 (Q9NQS3)
Nectin-3 (CDw113) (Nectin cell adhesion molecule 3) (Poliovirus receptor-related protein 3) (CD antigen CD113)
Gene: NECTIN3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.90 1.00 0.952

The method score is based on:

Property Details
Experiments 21982860, 26186194, 28514442, 33961781, 22902367, 23758976
Identification Methods pull down, affinity chromatography technology, surface plasmon resonance, protein array, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains C2-set_2~C2-set_2, C2-set_2~V-set, V-set~V-set
Common GO terms GO:0005886 - plasma membrane
GO:0005911 - cell-cell junction
GO:0007156 - homophilic cell adhesion via plasma membrane adhesion molecules
GO:0009566 - fertilization
GO:0042803 - protein homodimerization activity
and 3 others

more...

Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 538
Hs

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Last updated: 15 Jul 2024