HitPredict

Interactor 1: NECT2 (Q92692)
Nectin-2 (Herpes virus entry mediator B) (Herpesvirus entry mediator B) (HveB) (Nectin cell adhesion molecule 2) (Poliovirus receptor-related protein 2) (CD antigen CD112)
Gene: NECTIN2

Interactor 2: CLC4A (Q9UMR7)
C-type lectin domain family 4 member A (C-type lectin DDB27) (C-type lectin superfamily member 6) (Dendritic cell immunoreceptor) (Lectin-like immunoreceptor) (CD antigen CD367)
Gene: CLEC4A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 538 Hs			1 237
+	Hs
		1343564 NECT3_HUMAN (30-389): 3.83e-72: 241: 25.00		CLC4A_HUMAN (1-237): 9.8e-70: 215: 100.00
+	Hs
		545187 PVR_HUMAN (25-441): 3.32e-61: 209: 42.72		CLC4A_HUMAN (1-237): 9.8e-70: 215: 100.00
+	Hs
		1268547 PXDN_HUMAN (245-533): 1.24e-44: 171: 12.33		CLC4A_HUMAN (1-237): 9.8e-70: 215: 100.00
+	Hs
		530196 NCAM1_HUMAN (33-529): 2.22e-37: 149: 13.30		CLC4A_HUMAN (1-237): 9.8e-70: 215: 100.00
+	Hs
		1031178 PTK7_HUMAN (4-527): 3.59e-35: 142: 14.13		CLC4A_HUMAN (1-237): 9.8e-70: 215: 100.00
+	Hs
		1031177 PTK7_HUMAN (4-527): 3.59e-35: 142: 14.13		CLC4E_HUMAN (25-236): 9.51e-58: 184: 34.58
+	Hs
		149946 NCAM1_HUMAN (33-529): 2.22e-37: 149: 13.30		NCAN_HUMAN (86-232): 2.02e-47: 169: 27.33
+	Hs
		299599 LRIG2_HUMAN (161-392): 3.45e-32: 133: 16.19		CLC4E_HUMAN (25-236): 9.51e-58: 184: 34.58
+	Hs
		1263883 LRIG1_HUMAN (153-427): 4.08e-34: 139: 14.14		CLC4D_HUMAN (31-237): 3.03e-54: 175: 33.33
+	Hs
		299573 LRIG2_HUMAN (161-392): 3.45e-32: 133: 16.19		CLC4D_HUMAN (31-237): 3.03e-54: 175: 33.33
+	Hs
		1357318 ROBO1_HUMAN (333-538): 1.79e-18: 91.7: 8.92		CLC4A_HUMAN (1-237): 9.8e-70: 215: 100.00
+	Hs
		1294928 KIRR1_HUMAN (33-363): 7.38e-16: 82.9: 16.72		CLC4A_HUMAN (1-237): 9.8e-70: 215: 100.00
+	Dr
		60058 Q8UVD6_DANRE (11-493): 1.37e-33: 138: 16.00		A4JYN2_DANRE (85-232): 1.12e-43: 158: 23.18
+	Hs
		1100785 LRIG1_HUMAN (153-427): 4.08e-34: 139: 14.14		CL12B_HUMAN (1-232): 5.06e-45: 153: 17.82
+	Hs
		299565 LRIG2_HUMAN (161-392): 3.45e-32: 133: 16.19		CL12B_HUMAN (1-232): 5.06e-45: 153: 17.82
+	Hs
		1245267 CADM4_HUMAN (267-538): 2.9e-12: 70.5: 11.03		CLC4A_HUMAN (1-237): 9.8e-70: 215: 100.00
+	Hs
		644626 LRIG1_HUMAN (153-427): 4.08e-34: 139: 14.14		NKG2A_HUMAN (2-233): 1.65e-40: 140: 16.81
+	Hs
		1166419 SIG12_HUMAN (31-354): 8.23e-22: 101: 15.07		CLC4G_HUMAN (70-232): 1.34e-39: 139: 27.22