HitPredict

Interactor 1: PGTA (Q92696)
Geranylgeranyl transferase type-2 subunit alpha (EC 2.5.1.60) (Geranylgeranyl transferase type II subunit alpha) (Rab geranyl-geranyltransferase subunit alpha) (Rab GG transferase alpha) (Rab GGTase alpha) (Rab geranylgeranyltransferase subunit alpha)
Gene: RABGGTA

Interactor 2: RAB7B (Q96AH8)
Ras-related protein Rab-7b
Gene: RAB7B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.50	0.574

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 567 Hs			1 199
+	Hs
		918923 PGTA_HUMAN (1-567): 4.32e-174: 506: 100.00		RAB1A_HUMAN (1-199): 5.66e-81: 241: 34.63
+	Hs
		1269153 PGTA_HUMAN (1-567): 4.32e-174: 506: 100.00		RAB1B_HUMAN (1-199): 1.76e-80: 239: 34.80
+	Hs
		1259985 PGTA_HUMAN (1-567): 4.32e-174: 506: 100.00		RAB2B_HUMAN (5-196): 3.46e-77: 231: 32.64
+	Hs
		894786 PGTA_HUMAN (1-567): 4.32e-174: 506: 100.00		RAB8A_HUMAN (1-197): 1.26e-74: 225: 31.68
+	Hs
		845648 PGTA_HUMAN (1-567): 4.32e-174: 506: 100.00		RAB9A_HUMAN (9-199): 6.73e-46: 152: 42.64
+	Hs
		1269156 PGTA_HUMAN (1-567): 4.32e-174: 506: 100.00		RAB9B_HUMAN (5-199): 2.55e-44: 147: 40.91
+	Hs
		591964 PGTA_HUMAN (1-567): 4.32e-174: 506: 100.00		RAB4A_HUMAN (9-177): 1.95e-35: 125: 39.41
+	Hs
		1044506 PGTA_HUMAN (1-567): 4.32e-174: 506: 100.00		RAB32_HUMAN (9-199): 4.86e-35: 124: 35.32
+	Hs
		826423 FNTA_HUMAN (25-243): 4.73e-64: 216: 23.74		RAB2B_HUMAN (5-196): 3.46e-77: 231: 32.64
+	Hs
		1049954 SCRIB_HUMAN (199-565): 4.75e-46: 176: 17.01		RAB35_HUMAN (1-199): 1.83e-86: 255: 34.15
+	Hs
		1070466 NISCH_HUMAN (349-559): 4.53e-41: 161: 24.54		RAB35_HUMAN (1-199): 1.83e-86: 255: 34.15
+	Hs
		914066 SCRIB_HUMAN (199-565): 4.75e-46: 176: 17.01		RB11A_HUMAN (2-199): 7.94e-76: 228: 25.00
+	Dm
		185517 Q9W501_DROME (21-209): 6.03e-45: 165: 23.47		O18332_DROME (2-199): 5.7e-77: 231: 34.80
+	Dm
		284087 Q9VR31_DROME (25-302): 4.37e-65: 217: 23.93		RAB7_DROME (1-195): 1.52e-55: 176: 44.95
+	Sc
		701802 PGTA_YEAST (1-321): 1.42e-71: 234: 26.65		YPT7_YEAST (1-198): 4.62e-48: 157: 42.23
+	Dm
		185722 Q9W501_DROME (21-209): 6.03e-45: 165: 23.47		O18335_DROME (2-199): 1.83e-74: 225: 26.42
+	Hs
		914475 NISCH_HUMAN (349-559): 4.53e-41: 161: 24.54		RB11A_HUMAN (2-199): 7.94e-76: 228: 25.00
+	Hs
		845362 NISCH_HUMAN (349-559): 4.53e-41: 161: 24.54		RAB7A_HUMAN (1-189): 8.32e-61: 190: 50.00
+	Hs
		845813 NISCH_HUMAN (349-559): 4.53e-41: 161: 24.54		RAB9A_HUMAN (9-199): 6.73e-46: 152: 42.64
+	Hs
		592070 NISCH_HUMAN (349-559): 4.53e-41: 161: 24.54		RAB4A_HUMAN (9-177): 1.95e-35: 125: 39.41