Interactor 1: WASL (O00401)
Actin nucleation-promoting factor WASL (Neural Wiskott-Aldrich syndrome protein) (N-WASP)
Gene: WASL

Interactor 2: GRB2 (P62993)
Growth factor receptor-bound protein 2 (Adapter protein GRB2) (Protein Ash) (SH2/SH3 adapter GRB2)
Gene: GRB2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 0.60 0.759

The method score is based on:

Property Details
Experiments 10781580, 25416956, 28514442, 27107012, 31980649, 33961781, 20936779, 21706016, 17474147, unassigned2173
Identification Methods pull down, two hybrid, affinity chromatography technology, peptide array, two hybrid prey pooling approach, two hybrid array, validated two hybrid, barcode fusion genetics two hybrid, anti tag coimmunoprecipitation, two hybrid pooling approach
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0070062 - extracellular exosome
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 505
Hs

1 217
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024