HitPredict

Interactor 1: ESR2 (Q92731)
Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A member 2)
Gene: ESR2

Interactor 2: UTP4 (Q969X6)
U3 small nucleolar RNA-associated protein 4 homolog (Cirhin) (UTP4 small subunit processome component)
Gene: UTP4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29509190
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0006355 - regulation of DNA-templated transcription
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 530 Hs			1 686
+	Hs
		370161 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		UTP4_HUMAN (1-686): 1.05e-147: 446: 98.98
+	Hs
		1016308 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		TBL3_HUMAN (154-681): 9.78e-51: 191: 10.06
+	Hs
		369488 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		TBL3_HUMAN (154-681): 9.78e-51: 191: 10.06
+	Hs
		1269936 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		WDR3_HUMAN (402-635): 3.61e-32: 135: 12.86
+	Hs
		369932 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		WDR5B_HUMAN (2-221): 3.77e-50: 179: 14.91
+	Hs
		1074801 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		TAF5_HUMAN (2-271): 1.71e-22: 104: 19.85
+	Hs
		903403 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		WDR5_HUMAN (514-677): 1.36e-20: 95.3: 12.20
+	Hs
		1269559 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		SKI8_HUMAN (98-315): 9.01e-19: 89.5: 15.77
+	Hs
		370713 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		WDR3_HUMAN (402-635): 3.61e-32: 135: 12.86
+	Hs
		725512 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		COPB2_HUMAN (478-612): 1.11e-12: 73.4: 17.04
+	Hs
		1269746 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		NLE1_HUMAN (563-681): 2.39e-11: 68.7: 10.83
+	Hs
		377280 GCR_HUMAN (3-495): 1.12e-103: 330: 22.64		TBL3_HUMAN (154-681): 9.78e-51: 191: 10.06
+	Hs
		369669 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		TAF5_HUMAN (2-271): 1.71e-22: 104: 19.85
+	Hs
		369305 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		WDR5_HUMAN (514-677): 1.36e-20: 95.3: 12.20
+	Hs
		370394 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		SKI8_HUMAN (98-315): 9.01e-19: 89.5: 15.77
+	Hs
		782550 HNF4A_HUMAN (94-502): 1.21e-107: 331: 23.30		TAF5_HUMAN (2-271): 1.71e-22: 104: 19.85
+	Hs
		782513 HNF4A_HUMAN (94-502): 1.21e-107: 331: 23.30		WDR5_HUMAN (514-677): 1.36e-20: 95.3: 12.20
+	Mm
		903664 ERR2_MOUSE (69-499): 5.26e-107: 328: 31.11		WDR5_MOUSE (514-677): 1.36e-20: 95.3: 12.20
+	Hs
		487288 ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59		WDR5_HUMAN (514-677): 1.36e-20: 95.3: 12.20