HitPredict

Interactor 1: WASL (O00401)
Actin nucleation-promoting factor WASL (Neural Wiskott-Aldrich syndrome protein) (N-WASP)
Gene: WASL

Interactor 2: SRC8 (Q14247)
Src substrate cortactin (Amplaxin) (Oncogene EMS1)
Gene: CTTN

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.624

Property	Details
Experiments	11830518, 12672817
Identification Methods	far western blotting, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0030027 - lamellipodium
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 505 Hs			1 550
+	Hs
		203224 SYNJ1_HUMAN (4-500): 4.14e-62: 222: 14.85		MYO1E_HUMAN (165-549): 3.1e-44: 170: 15.01
+	Hs
		203262 SYNJ1_HUMAN (4-500): 4.14e-62: 222: 14.85		PACN2_HUMAN (176-550): 4.93e-40: 153: 15.37
+	Rn
		192356 SYNJ1_RAT (4-505): 7.74e-69: 241: 13.31		SH3G3_RAT (365-549): 5.6e-32: 128: 19.36
+	Rn
		193638 SYNJ1_RAT (4-505): 7.74e-69: 241: 13.31		SH3G1_RAT (365-549): 1.58e-31: 127: 17.01
+	Rn
		192354 SYNJ1_RAT (4-505): 7.74e-69: 241: 13.31		SH3G2_RAT (365-549): 8.86e-31: 124: 17.28
+	Hs
		203251 SYNJ1_HUMAN (4-500): 4.14e-62: 222: 14.85		PACN1_HUMAN (241-549): 2.37e-31: 128: 16.86
+	Hs
		203249 SYNJ1_HUMAN (4-500): 4.14e-62: 222: 14.85		SH3G2_HUMAN (365-549): 1.87e-31: 126: 17.28
+	Hs
		203248 SYNJ1_HUMAN (4-500): 4.14e-62: 222: 14.85		SH3G1_HUMAN (365-549): 6.52e-31: 125: 17.01
+	Mm
		88459 D3Z656_MOUSE (4-505): 5.91e-61: 218: 13.01		SH3G2_MOUSE (365-549): 4.6e-31: 125: 17.80
+	Mm
		88460 D3Z656_MOUSE (4-505): 5.91e-61: 218: 13.01		SH3G3_MOUSE (365-549): 4.53e-31: 125: 19.89
+	Dm
		1361428 Q9VAT0_DROME (1-504): 8.78e-57: 199: 31.37		DBNL_DROME (208-549): 6.56e-34: 136: 20.53
+	Rn
		192744 SYNJ1_RAT (4-505): 7.74e-69: 241: 13.31		SRBS2_RAT (452-549): 1.44e-11: 69.6: 22.00
+	Hs
		166056 SYNJ2_HUMAN (3-471): 6.56e-60: 215: 14.85		ITSN2_HUMAN (398-548): 1.14e-18: 92.3: 17.88
+	Hs
		203228 SYNJ1_HUMAN (4-500): 4.14e-62: 222: 14.85		ITSN1_HUMAN (165-548): 1.66e-14: 78.9: 11.99
+	Hs
		203191 SYNJ1_HUMAN (4-500): 4.14e-62: 222: 14.85		VINEX_HUMAN (254-546): 4.43e-13: 73.9: 13.51
+	Hs
		166049 SYNJ2_HUMAN (3-471): 6.56e-60: 215: 14.85		ITSN1_HUMAN (165-548): 1.66e-14: 78.9: 11.99
+	Hs
		203192 SYNJ1_HUMAN (4-500): 4.14e-62: 222: 14.85		SRBS2_HUMAN (447-549): 1.56e-11: 69.2: 21.91
+	Dm
		112580 Q9VAT0_DROME (1-504): 8.78e-57: 199: 31.37		M9ND00_DROME (219-547): 1.48e-10: 66.4: 16.67
+	Hs
		302308 SC31A_HUMAN (10-495): 1.62e-51: 191: 10.39		STAM1_HUMAN (416-546): 2.82e-13: 74.4: 21.83
+	Dm
		1361426 Q9VAT0_DROME (1-504): 8.78e-57: 199: 31.37		Q9VIF7_DROME (219-547): 4.16e-10: 64.9: 16.67