HitPredict

Interactor 1: ESR2 (Q92731)
Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A member 2)
Gene: ESR2

Interactor 2: SPF45 (Q96I25)
Splicing factor 45 (45 kDa-splicing factor) (RNA-binding motif protein 17)
Gene: RBM17

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29509190
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 530 Hs			1 401
+	Mm
		139022 ESR2_MOUSE (1-530): 5.25e-160: 467: 88.68		RBM39_MOUSE (88-394): 1.33e-72: 237: 13.76
+	Hs
		1054478 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		RBM39_HUMAN (88-394): 1.66e-72: 237: 13.76
+	Hs
		369602 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		RBM39_HUMAN (88-394): 1.66e-72: 237: 13.76
+	Hs
		487679 ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59		SPF45_HUMAN (1-401): 4.66e-158: 452: 100.00
+	Hs
		1269983 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		MAN1_HUMAN (292-395): 2.1e-27: 116: 16.96
+	Hs
		369016 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		U2AF2_HUMAN (244-397): 2.42e-36: 140: 23.93
+	Hs
		212165 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		HTSF1_HUMAN (305-388): 4.02e-17: 85.4: 27.78
+	Hs
		370763 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		MAN1_HUMAN (292-395): 2.1e-27: 116: 16.96
+	Hs
		414503 PRGR_HUMAN (149-459): 2.26e-41: 161: 32.82		RBM39_HUMAN (88-394): 1.66e-72: 237: 13.76
+	Hs
		414527 PRGR_HUMAN (149-459): 2.26e-41: 161: 32.82		PUF60_HUMAN (131-398): 8.05e-33: 131: 16.67
+	Hs
		487146 ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59		U2AF2_HUMAN (244-397): 2.42e-36: 140: 23.93
+	Hs
		487822 ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59		PUF60_HUMAN (131-398): 8.05e-33: 131: 16.67