HitPredict

Interactor 1: ESR2 (Q92731)
Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A member 2)
Gene: ESR2

Interactor 2: ARHGH (Q96PE2)
Rho guanine nucleotide exchange factor 17 (164 kDa Rho-specific guanine-nucleotide exchange factor) (p164-RhoGEF) (p164RhoGEF) (Tumor endothelial marker 4)
Gene: ARHGEF17

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	29509190
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 530 Hs			1 2063
+	Hs
		167102 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		ARHGB_HUMAN (529-1767): 7.24e-101: 361: 13.52
+	Hs
		1269288 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		ARHG2_HUMAN (858-1740): 6.2e-104: 360: 14.74
+	Hs
		1269784 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		ITSN2_HUMAN (684-1531): 1.73e-91: 333: 15.69
+	Hs
		506632 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		BCR_HUMAN (661-1507): 8.04e-93: 333: 18.96
+	Hs
		370229 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		FGD4_HUMAN (872-1625): 8.54e-111: 374: 15.89
+	Hs
		167059 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		ARHGB_HUMAN (529-1767): 7.24e-101: 361: 13.52
+	Hs
		370149 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		ARHG2_HUMAN (858-1740): 6.2e-104: 360: 14.74
+	Hs
		279882 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		TRIO_HUMAN (1049-1752): 4.34e-78: 291: 14.01
+	Hs
		369863 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		DNMBP_HUMAN (539-1741): 1.41e-93: 338: 15.90
+	Hs
		370586 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		ITSN2_HUMAN (684-1531): 1.73e-91: 333: 15.69
+	Hs
		1254025 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		PREX1_HUMAN (1039-1431): 1.2e-74: 278: 23.91
+	Hs
		370063 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		PREX1_HUMAN (1039-1431): 1.2e-74: 278: 23.91
+	Hs
		377558 GCR_HUMAN (3-495): 1.12e-103: 330: 22.64		ARHG2_HUMAN (858-1740): 6.2e-104: 360: 14.74
+	Hs
		370459 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		ECT2_HUMAN (984-1451): 4.6e-72: 263: 20.70
+	Hs
		377746 GCR_HUMAN (3-495): 1.12e-103: 330: 22.64		ITSN2_HUMAN (684-1531): 1.73e-91: 333: 15.69
+	Hs
		200765 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		ARHG9_HUMAN (1024-1334): 1.48e-67: 240: 20.19
+	Hs
		611508 NR4A1_HUMAN (7-501): 3.18e-101: 318: 25.30		ARGAL_HUMAN (1712-2019): 7.76e-81: 296: 25.24
+	Hs
		377520 GCR_HUMAN (3-495): 1.12e-103: 330: 22.64		PREX1_HUMAN (1039-1431): 1.2e-74: 278: 23.91
+	Hs
		370679 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		VAV3_HUMAN (1046-1323): 6.41e-18: 92.8: 27.72
+	Hs
		369418 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		ECT2L_HUMAN (1061-1335): 2.33e-14: 81.3: 24.57