HitPredict

Interactor 1: ESR2 (Q92731)
Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A member 2)
Gene: ESR2

Interactor 2: TCPH (Q99832)
T-complex protein 1 subunit eta (TCP-1-eta) (CCT-eta) (Chaperonin containing T-complex polypeptide 1 subunit 7) (HIV-1 Nef-interacting protein) [Cleaved into: T-complex protein 1 subunit eta, N-terminally processed]
Gene: CCT7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.50	0.521

Property	Details
Experiments	29509190, 25604459
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 530 Hs			1 543
+	Hs
		370293 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		TCPH_HUMAN (1-543): 0: 647: 100.00
+	Hs
		826802 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		TCPG_HUMAN (1-541): 0: 577: 31.09
+	Hs
		821341 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		TCPE_HUMAN (3-527): 0: 557: 29.59
+	Hs
		573400 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		TCPA_HUMAN (2-533): 0: 544: 34.54
+	Hs
		369183 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		TCPG_HUMAN (1-541): 0: 577: 31.09
+	Hs
		369172 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		TCPE_HUMAN (3-527): 0: 557: 29.59
+	Hs
		611495 NR4A1_HUMAN (7-501): 3.18e-101: 318: 25.30		TCPH_HUMAN (1-543): 0: 647: 100.00
+	Hs
		573130 NR4A1_HUMAN (7-501): 3.18e-101: 318: 25.30		TCPA_HUMAN (2-533): 0: 544: 34.54
+	Hs
		843313 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		TCPD_HUMAN (24-520): 4.05e-90: 288: 33.79
+	Hs
		369209 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		TCPD_HUMAN (24-520): 4.05e-90: 288: 33.79
+	Hs
		487113 ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59		TCPA_HUMAN (2-533): 0: 544: 34.54
+	Hs
		487242 ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59		TCPD_HUMAN (24-520): 4.05e-90: 288: 33.79