HitPredict

Interactor 1: ESR2 (Q92731)
Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A member 2)
Gene: ESR2

Interactor 2: SENP3 (Q9H4L4)
Sentrin-specific protease 3 (EC 3.4.22.-) (SUMO-1-specific protease 3) (Sentrin/SUMO-specific protease SENP3)
Gene: SENP3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	29509190, 21182203
Identification Methods	affinity chromatography technology, cosedimentation through density gradient
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 530 Hs			1 574
+	Hs
		370431 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		SENP3_HUMAN (1-574): 0: 683: 100.00
+	Mm
		1142731 ERR2_MOUSE (69-499): 5.26e-107: 328: 31.11		SENP3_MOUSE (1-574): 0: 762: 94.60
+	Hs
		377683 GCR_HUMAN (3-495): 1.12e-103: 330: 22.64		SENP3_HUMAN (1-574): 0: 683: 100.00
+	Hs
		874394 NR1H2_HUMAN (49-499): 2.78e-103: 319: 20.86		SENP3_HUMAN (1-574): 0: 683: 100.00
+	Hs
		370202 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		SENP5_HUMAN (237-572): 8.14e-102: 326: 45.99
+	Hs
		487774 ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59		SENP2_HUMAN (116-572): 7.43e-139: 417: 23.98