HitPredict

Interactor 1: ESR2 (Q92731)
Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A member 2)
Gene: ESR2

Interactor 2: SMRCD (Q9H4L7)
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.4.12) (ATP-dependent helicase 1) (hHEL1)
Gene: SMARCAD1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	25604459
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 530 Hs			1 1026
+	Hs
		847036 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		SMCA4_HUMAN (96-1024): 0: 693: 26.54
+	Hs
		846832 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		SMCA2_HUMAN (55-1024): 0: 689: 25.05
+	Hs
		1269810 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		CHD7_HUMAN (23-1021): 0: 683: 22.57
+	Hs
		369214 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		SMCA4_HUMAN (96-1024): 0: 693: 26.54
+	Hs
		369213 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		SMCA2_HUMAN (55-1024): 0: 689: 25.05
+	Hs
		1269673 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		CHD8_HUMAN (181-1021): 0: 641: 23.28
+	Hs
		370607 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		CHD7_HUMAN (23-1021): 0: 683: 22.57
+	Hs
		1018616 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		CHD3_HUMAN (338-1022): 0: 621: 27.64
+	Hs
		370065 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		CHD6_HUMAN (61-1021): 0: 664: 22.13
+	Hs
		369729 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		CHD9_HUMAN (79-1021): 0: 651: 22.17
+	Hs
		151509 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		CHD2_HUMAN (33-1022): 0: 594: 22.15
+	Hs
		229452 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		SMCA5_HUMAN (353-1021): 0: 594: 29.60
+	Hs
		370482 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		CHD8_HUMAN (181-1021): 0: 641: 23.28
+	Hs
		587141 RXRA_HUMAN (13-502): 1.6e-119: 361: 25.71		SMCA4_HUMAN (96-1024): 0: 693: 26.54
+	Hs
		782504 HNF4A_HUMAN (94-502): 1.21e-107: 331: 23.30		SMCA4_HUMAN (96-1024): 0: 693: 26.54
+	Hs
		782503 HNF4A_HUMAN (94-502): 1.21e-107: 331: 23.30		SMCA2_HUMAN (55-1024): 0: 689: 25.05
+	Hs
		587181 RXRA_HUMAN (13-502): 1.6e-119: 361: 25.71		CHD9_HUMAN (79-1021): 0: 651: 22.17
+	Hs
		369451 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		ERCC6_HUMAN (21-1021): 0: 595: 20.53
+	Hs
		151470 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		CHD2_HUMAN (33-1022): 0: 594: 22.15
+	Hs
		229273 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		SMCA5_HUMAN (353-1021): 0: 594: 29.60