HitPredict

Interactor 1: WASL (O00401)
Actin nucleation-promoting factor WASL (Neural Wiskott-Aldrich syndrome protein) (N-WASP)
Gene: WASL

Interactor 2: ITSN2 (Q9NZM3)
Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein)
Gene: ITSN2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	22558309
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0070062 - extracellular exosome
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 505 Hs			1 1697
+	Hs
		166056 SYNJ2_HUMAN (3-471): 6.56e-60: 215: 14.85		ITSN2_HUMAN (1-1697): 0: 969: 100.00
+	Hs
		790688 WASP_HUMAN (16-313): 7.4e-38: 147: 44.41		ITSN2_HUMAN (1-1697): 0: 969: 100.00
+	Hs
		203228 SYNJ1_HUMAN (4-500): 4.14e-62: 222: 14.85		ITSN1_HUMAN (2-1693): 0: 863: 56.23
+	Hs
		166049 SYNJ2_HUMAN (3-471): 6.56e-60: 215: 14.85		ITSN1_HUMAN (2-1693): 0: 863: 56.23
+	Hs
		257713 ANR17_HUMAN (144-483): 4.19e-18: 90.2: 14.57		ITSN2_HUMAN (1-1697): 0: 969: 100.00
+	Hs
		790676 WASP_HUMAN (16-313): 7.4e-38: 147: 44.41		ITSN1_HUMAN (2-1693): 0: 863: 56.23
+	Hs
		126936 WASL_HUMAN (378-485): 2.86e-29: 122: 100.00		ITSN1_HUMAN (2-1693): 0: 863: 56.23
+	Rn
		94091 F1LSG0_RAT (379-485): 2.85e-30: 125: 95.33		ITSN1_RAT (2-1693): 0: 854: 56.08
+	Mm
		1225213 DEN1A_MOUSE (143-490): 6.46e-22: 101: 17.53		ITSN1_MOUSE (2-1693): 0: 861: 56.37
+	Rn
		1126747 SYNJ1_RAT (4-505): 7.74e-69: 241: 13.31		Q5JC29_RAT (7-410): 1.28e-31: 136: 18.55
+	Dm
		112580 Q9VAT0_DROME (1-504): 8.78e-57: 199: 31.37		M9ND00_DROME (1-447): 2.52e-32: 139: 14.35
+	Hs
		203230 SYNJ1_HUMAN (4-500): 4.14e-62: 222: 14.85		SH319_HUMAN (1035-1211): 6.54e-11: 69.3: 28.26
+	Dm
		1361426 Q9VAT0_DROME (1-504): 8.78e-57: 199: 31.37		Q9VIF7_DROME (796-1047): 2e-14: 81: 20.08
+	Hs
		195990 PLXB1_HUMAN (277-461): 1.76e-27: 119: 25.82		ARHGC_HUMAN (1189-1535): 2.93e-21: 103: 27.07
+	Hs
		167053 PLXB1_HUMAN (277-461): 1.76e-27: 119: 25.82		ARHGB_HUMAN (1207-1441): 1.17e-20: 101: 30.08
+	Hs
		855816 TITIN_HUMAN (345-474): 5.12e-09: 61.3: 17.56		VAV2_HUMAN (614-1182): 8.45e-12: 72.6: 12.07