HitPredict

Interactor 1: ESR2 (Q92731)
Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A member 2)
Gene: ESR2

Interactor 2: EXOS5 (Q9NQT4)
Exosome complex component RRP46 (Chronic myelogenous leukemia tumor antigen 28) (Exosome component 5) (Ribosomal RNA-processing protein 46) (p12B)
Gene: EXOSC5

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29509190
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 530 Hs			1 235
+	Hs
		1269690 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		EXOS4_HUMAN (9-235): 1.12e-75: 230: 26.47
+	Hs
		1269316 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		EXOS8_HUMAN (4-234): 4.65e-59: 189: 19.26
+	Hs
		370496 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		EXOS4_HUMAN (9-235): 1.12e-75: 230: 26.47
+	Hs
		370504 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		EXOS5_HUMAN (1-235): 2.29e-66: 206: 100.00
+	Hs
		1063748 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		EXOS7_HUMAN (1-233): 2.23e-46: 157: 15.52
+	Hs
		1130039 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		EXOS6_HUMAN (9-228): 2.79e-42: 146: 25.41
+	Hs
		370165 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		EXOS8_HUMAN (4-234): 4.65e-59: 189: 19.26
+	Hs
		369631 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		EXOS7_HUMAN (1-233): 2.23e-46: 157: 15.52
+	Hs
		659731 RXRB_HUMAN (96-498): 2.03e-108: 335: 27.05		EXOS8_HUMAN (4-234): 4.65e-59: 189: 19.26
+	Hs
		510023 ERR1_HUMAN (85-497): 1.88e-112: 342: 35.65		EXOS6_HUMAN (9-228): 2.79e-42: 146: 25.41
+	Hs
		914648 ERR3_HUMAN (60-499): 2.69e-106: 327: 30.29		EXOS7_HUMAN (1-233): 2.23e-46: 157: 15.52
+	Mm
		1142678 ERR2_MOUSE (69-499): 5.26e-107: 328: 31.11		EXOS6_MOUSE (4-228): 2.16e-45: 154: 22.49