HitPredict

Interactor 1: ESR2 (Q92731)
Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A member 2)
Gene: ESR2

Interactor 2: PRR12 (Q9ULL5)
Proline-rich protein 12
Gene: PRR12

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29509190
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 530 Hs			1 2036
+	Hs
		1101056 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		QSER1_HUMAN (298-2030): 2.6e-51: 202: 13.43
+	Hs
		554348 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		MUC1_HUMAN (1336-1852): 5e-18: 93.5: 12.57
+	Hs
		1056909 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		MDC1_HUMAN (92-963): 7.61e-17: 89.7: 11.38
+	Hs
		1057780 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		NCOA6_HUMAN (171-1295): 3.55e-16: 87.6: 8.34
+	Hs
		1264774 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		TITIN_HUMAN (1009-1921): 7.14e-12: 73.7: 10.37
+	Hs
		1138792 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		PPRC1_HUMAN (206-1313): 9.67e-12: 72.9: 10.65
+	Hs
		1243831 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		KMT2C_HUMAN (1353-1854): 1.66e-11: 72.4: 11.92
+	Hs
		1269667 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		MUC5B_HUMAN (808-1869): 2.19e-11: 71.8: 9.37
+	Hs
		311824 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		TACC2_HUMAN (1081-1934): 2.09e-11: 71.8: 9.44
+	Hs
		1269413 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		CIC_HUMAN (29-608): 2.88e-11: 71.4: 9.14
+	Hs
		517813 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		NFH_HUMAN (1053-1574): 3.25e-11: 70.9: 12.45
+	Hs
		1186078 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		MICA3_HUMAN (664-1403): 1.13e-10: 69.6: 14.15
+	Hs
		1269948 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		SRRM2_HUMAN (1115-1954): 3.65e-10: 67.9: 8.65
+	Hs
		1270066 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		PCLO_HUMAN (54-1687): 2e-09: 65.6: 8.48
+	Hs
		577676 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		SON_HUMAN (1329-1560): 2.13e-09: 65.2: 23.14
+	Hs
		368927 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		MUC1_HUMAN (1336-1852): 5e-18: 93.5: 12.57
+	Hs
		369607 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		MDC1_HUMAN (92-963): 7.61e-17: 89.7: 11.38
+	Hs
		369612 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		NCOA6_HUMAN (171-1295): 3.55e-16: 87.6: 8.34
+	Hs
		370040 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		KMT2C_HUMAN (1353-1854): 1.66e-11: 72.4: 11.92
+	Hs
		368952 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		SON_HUMAN (1329-1560): 2.13e-09: 65.2: 23.14