HitPredict

Interactor 1: ESR2 (Q92731)
Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A member 2)
Gene: ESR2

Interactor 2: MACF1 (Q9UPN3)
Microtubule-actin cross-linking factor 1, isoforms 1/2/3/4/5 (620 kDa actin-binding protein) (ABP620) (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha)
Gene: MACF1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	29509190
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 530 Hs			1 7388
+	Hs
		885285 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		EPIPL_HUMAN (1538-2789): 1.49e-35: 154: 13.15
+	Hs
		1068618 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		PLEC_HUMAN (2677-3656): 8.53e-27: 124: 8.13
+	Hs
		551794 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		DESP_HUMAN (2737-3775): 9.21e-27: 124: 8.65
+	Hs
		369273 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		EPIPL_HUMAN (1538-2789): 1.49e-35: 154: 13.15
+	Hs
		993279 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		ACTN3_HUMAN (5633-6111): 4.77e-17: 92.1: 12.20
+	Hs
		974119 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		DYST_HUMAN (478-1511): 2.31e-12: 77.1: 9.72
+	Hs
		368926 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		DESP_HUMAN (2737-3775): 9.21e-27: 124: 8.65
+	Hs
		369641 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		PLEC_HUMAN (2677-3656): 8.53e-27: 124: 8.13
+	Hs
		164649 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		SPTN2_HUMAN (3436-4815): 1.06e-11: 74.8: 9.59
+	Hs
		809148 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		UTRN_HUMAN (428-1437): 8.81e-11: 71.9: 13.98
+	Hs
		1059246 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		GOGB1_HUMAN (6684-7219): 2.29e-10: 70.5: 9.23
+	Hs
		521591 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		ACTN1_HUMAN (921-1398): 1.47e-10: 70.5: 9.07
+	Hs
		1045473 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		SPTN1_HUMAN (433-1344): 7.43e-10: 68.8: 13.39
+	Hs
		370043 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		SYNE1_HUMAN (343-1742): 3.05e-13: 80.2: 8.97
+	Hs
		369446 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		DYST_HUMAN (478-1511): 2.31e-12: 77.1: 9.72
+	Hs
		369420 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		SPTB2_HUMAN (6378-7134): 6.05e-11: 72.5: 13.80
+	Hs
		369158 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		UTRN_HUMAN (428-1437): 8.81e-11: 71.9: 13.98
+	Hs
		368893 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		ACTN1_HUMAN (921-1398): 1.47e-10: 70.5: 9.07
+	Hs
		369619 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		GOGB1_HUMAN (6684-7219): 2.29e-10: 70.5: 9.23
+	Hs
		369568 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		SPTN1_HUMAN (433-1344): 7.43e-10: 68.8: 13.39