HitPredict

Interactor 1: ESR2 (Q92731)
Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A member 2)
Gene: ESR2

Interactor 2: MD1L1 (Q9Y6D9)
Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient 1-like protein 1) (MAD1-like protein 1) (Mitotic checkpoint MAD1 protein homolog) (HsMAD1) (hMAD1) (Tax-binding protein 181)
Gene: MAD1L1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29509190
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 530 Hs			1 718
+	Hs
		369789 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		MRCKA_HUMAN (164-708): 6.22e-43: 170: 17.69
+	Hs
		522631 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		MYH7_HUMAN (1-542): 2.2e-19: 95.8: 7.17
+	Hs
		724944 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		MYH9_HUMAN (286-715): 8.08e-18: 90.5: 13.86
+	Hs
		1269900 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		MYH13_HUMAN (1-429): 1.42e-13: 77: 10.83
+	Hs
		149132 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		CTRO_HUMAN (54-632): 5.17e-13: 75: 15.98
+	Hs
		1255114 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		DLG5_HUMAN (125-628): 3.83e-12: 72.3: 15.98
+	Hs
		1270044 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		MYH4_HUMAN (421-698): 1.91e-10: 66.6: 11.87
+	Hs
		551794 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		DESP_HUMAN (40-508): 1.22e-09: 64.2: 16.36
+	Hs
		1270038 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		MRCKB_HUMAN (1-389): 1.46e-09: 63.8: 11.96
+	Hs
		1268061 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		MY18A_HUMAN (44-521): 2.6e-09: 63: 15.87
+	Hs
		369096 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		MYH9_HUMAN (286-715): 8.08e-18: 90.5: 13.86
+	Hs
		368902 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		MYH6_HUMAN (300-716): 3.03e-16: 85.4: 12.86
+	Hs
		148263 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		CTRO_HUMAN (54-632): 5.17e-13: 75: 15.98
+	Hs
		370068 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		DLG5_HUMAN (125-628): 3.83e-12: 72.3: 15.98
+	Hs
		368926 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		DESP_HUMAN (40-508): 1.22e-09: 64.2: 16.36
+	Hs
		370819 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		MRCKB_HUMAN (1-389): 1.46e-09: 63.8: 11.96
+	Hs
		370120 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		MY18A_HUMAN (44-521): 2.6e-09: 63: 15.87
+	Hs
		587127 RXRA_HUMAN (13-502): 1.6e-119: 361: 25.71		MYH9_HUMAN (286-715): 8.08e-18: 90.5: 13.86
+	Hs
		659748 RXRB_HUMAN (96-498): 2.03e-108: 335: 27.05		MRCKB_HUMAN (1-389): 1.46e-09: 63.8: 11.96
+	Hs
		377068 GCR_HUMAN (3-495): 1.12e-103: 330: 22.64		DESP_HUMAN (40-508): 1.22e-09: 64.2: 16.36