HitPredict

Interactor 1: ESR2 (Q92731)
Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A member 2)
Gene: ESR2

Interactor 2: MYO16 (Q9Y6X6)
Unconventional myosin-XVI (Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 3) (Unconventional myosin-16)
Gene: MYO16

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	25604459
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 530 Hs			1 1858
+	Hs
		1269900 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		MYH13_HUMAN (382-1272): 0: 1038: 23.33
+	Hs
		64608 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		MYH7B_HUMAN (285-1273): 0: 1028: 22.75
+	Hs
		522631 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		MYH7_HUMAN (378-1303): 0: 1013: 23.76
+	Hs
		1270020 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		MYO5A_HUMAN (347-1279): 0: 1003: 25.97
+	Hs
		724944 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		MYH9_HUMAN (383-1304): 0: 975: 22.90
+	Hs
		1270044 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		MYH4_HUMAN (386-1273): 0: 960: 22.25
+	Hs
		370802 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		MYO5A_HUMAN (347-1279): 0: 1003: 25.97
+	Hs
		368902 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		MYH6_HUMAN (378-1303): 0: 975: 22.33
+	Hs
		369096 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		MYH9_HUMAN (383-1304): 0: 975: 22.90
+	Hs
		587127 RXRA_HUMAN (13-502): 1.6e-119: 361: 25.71		MYH9_HUMAN (383-1304): 0: 975: 22.90
+	Hs
		377795 GCR_HUMAN (3-495): 1.12e-103: 330: 22.64		MYH2_HUMAN (385-1273): 0: 965: 22.17
+	Hs
		1264038 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		MYO3B_HUMAN (404-1183): 2.96e-129: 442: 34.39
+	Hs
		297392 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		MYO1D_HUMAN (405-1164): 9.42e-96: 336: 29.96
+	Hs
		117783 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		MYO1C_HUMAN (413-1169): 4.64e-92: 326: 31.12
+	Hs
		1021687 ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00		MYO1E_HUMAN (404-1169): 1.36e-90: 323: 31.05
+	Hs
		117551 ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56		MYO1C_HUMAN (413-1169): 4.64e-92: 326: 31.12
+	Hs
		377299 GCR_HUMAN (3-495): 1.12e-103: 330: 22.64		MYO7A_HUMAN (404-1169): 1.05e-97: 353: 31.07
+	Hs
		297268 GCR_HUMAN (3-495): 1.12e-103: 330: 22.64		MYO1D_HUMAN (405-1164): 9.42e-96: 336: 29.96
+	Hs
		297279 ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59		MYO1D_HUMAN (405-1164): 9.42e-96: 336: 29.96
+	Hs
		117569 ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59		MYO1C_HUMAN (413-1169): 4.64e-92: 326: 31.12