HitPredict

Interactor 1: ARC1A (Q92747)
Actin-related protein 2/3 complex subunit 1A (SOP2-like protein)
Gene: ARPC1A

Interactor 2: DBNL (Q9UJU6)
Drebrin-like protein (Cervical SH3P7) (Cervical mucin-associated protein) (Drebrin-F) (HPK1-interacting protein of 55 kDa) (HIP-55) (SH3 domain-containing protein 7)
Gene: DBNL

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003779 - actin binding GO:0005829 - cytosol GO:0051015 - actin filament binding GO:0070062 - extracellular exosome
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 370 Hs			1 430
+	Hs
		1085020 ARC1A_HUMAN (1-370): 1.66e-89: 275: 100.00		DREB_HUMAN (3-379): 1.4e-59: 207: 29.19
+	Hs
		168799 ARC1B_HUMAN (1-369): 2.59e-83: 259: 68.10		DREB_HUMAN (3-379): 1.4e-59: 207: 29.19
+	Hs
		1052278 ARC1A_HUMAN (1-370): 1.66e-89: 275: 100.00		SRC8_HUMAN (120-430): 9.82e-34: 134: 25.71
+	Hs
		168792 ARC1B_HUMAN (1-369): 2.59e-83: 259: 68.10		SRC8_HUMAN (120-430): 9.82e-34: 134: 25.71
+	Hs
		903182 WDR5_HUMAN (175-363): 2.8e-38: 141: 14.87		MYO1E_HUMAN (147-429): 3.45e-33: 134: 14.84
+	Hs
		46284 A0A1W2PNV4_HUMAN (4-356): 3.05e-24: 106: 9.05		SRC8_HUMAN (120-430): 9.82e-34: 134: 25.71
+	Hs
		61736 SNR40_HUMAN (129-369): 1.6e-45: 161: 14.92		A6H8W8_HUMAN (70-428): 7.79e-15: 78.9: 10.65
+	Hs
		1288351 SNR40_HUMAN (129-369): 1.6e-45: 161: 14.92		ITSN2_HUMAN (79-428): 1.09e-14: 78.5: 9.41
+	Hs
		282820 CIAO1_HUMAN (2-131): 3.29e-23: 100: 13.82		NEBU_HUMAN (87-429): 3.31e-34: 138: 15.00
+	Sc
		551362 ARPC1_YEAST (96-365): 4.47e-12: 68.8: 12.68		ABP1_YEAST (131-428): 5.77e-16: 82: 18.59