HitPredict

Interactor 1: RORB (Q92753)
Nuclear receptor ROR-beta (Nuclear receptor RZR-beta) (Nuclear receptor subfamily 1 group F member 2) (Retinoid-related orphan receptor-beta)
Gene: RORB

Interactor 2: ZN587 (Q96SQ5)
Zinc finger protein 587
Gene: ZNF587

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	unassigned1304
Identification Methods	validated two hybrid, two hybrid array, two hybrid prey pooling approach
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 470 Hs			1 575
+	Hs
		1251749 RORB_HUMAN (1-470): 5.76e-139: 409: 100.00		ZN417_HUMAN (1-575): 0: 686: 98.09
+	Hs
		1123358 Q58EY0_HUMAN (14-470): 3.31e-134: 396: 100.00		ZN587_HUMAN (1-575): 0: 688: 100.00
+	Hs
		1123351 Q58EY0_HUMAN (14-470): 3.31e-134: 396: 100.00		ZN417_HUMAN (1-575): 0: 686: 98.09
+	Hs
		1061360 NR1D2_HUMAN (15-443): 2.58e-90: 288: 29.94		ZN587_HUMAN (1-575): 0: 688: 100.00
+	Hs
		992444 PPARA_HUMAN (8-461): 9.69e-73: 238: 22.27		ZN587_HUMAN (1-575): 0: 688: 100.00
+	Hs
		1155951 Q6NSM0_HUMAN (18-119): 1.19e-29: 121: 53.40		ZN587_HUMAN (1-575): 0: 688: 100.00
+	Hs
		824153 NR2C2_HUMAN (4-458): 3.08e-103: 321: 19.67		ZN546_HUMAN (48-174): 9.99e-33: 135: 18.90