Interactor 1: HDAC2 (Q92769)
Histone deacetylase 2 (HD2) (EC 3.5.1.98) (Protein deacylase HDAC2) (EC 3.5.1.-)
Gene: HDAC2
Interactor 2: MTA3 (Q9BTC8)
Metastasis-associated protein MTA3
Gene: MTA3
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.93 | 1.00 | 0.967 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 24981860, 12705869, 21258344, 30737378, 35271311, 23752268, 26949739, 26028330, 18451879 |
| Identification Methods | affinity chromatography technology, cross-linking study, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | ELM2~Hist_deacetyl, Hist_deacetyl~Myb_DNA-binding |
| Common GO terms | GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm and 7 others more... |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
