HitPredict

Interactor 1: HDAC2 (Q92769)
Histone deacetylase 2 (HD2) (EC 3.5.1.98) (Protein deacylase HDAC2) (EC 3.5.1.-)
Gene: HDAC2

Interactor 2: TXNIP (Q9H3M7)
Thioredoxin-interacting protein (Thioredoxin-binding protein 2) (Vitamin D3 up-regulated protein 1)
Gene: TXNIP

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.621

Property	Details
Experiments	29378950, 38270169
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005737 - cytoplasm GO:0009410 - response to xenobiotic stimulus
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 488 Hs			1 391
+	Hs
		1038706 HDAC1_HUMAN (1-443): 0: 642: 90.07		TXNIP_HUMAN (1-391): 1.4e-149: 430: 100.00
+	Hs
		1252805 HDAC2_HUMAN (1-488): 0: 707: 100.00		ARRD2_HUMAN (2-383): 5.07e-124: 365: 37.85
+	Hs
		177380 HDAC3_HUMAN (10-431): 0: 574: 58.26		TXNIP_HUMAN (1-391): 1.4e-149: 430: 100.00
+	Hs
		686023 HDAC2_HUMAN (1-488): 0: 707: 100.00		ARRB2_HUMAN (15-323): 2.03e-60: 202: 12.18
+	Hs
		685939 HDAC1_HUMAN (1-443): 0: 642: 90.07		ARRB2_HUMAN (15-323): 2.03e-60: 202: 12.18