HitPredict

Interactor 1: HDAC2 (Q92769)
Histone deacetylase 2 (HD2) (EC 3.5.1.98) (Protein deacylase HDAC2) (EC 3.5.1.-)
Gene: HDAC2

Interactor 2: SDS3 (Q9H7L9)
Sin3 histone deacetylase corepressor complex component SDS3 (45 kDa Sin3-associated polypeptide) (Suppressor of defective silencing 3 protein homolog)
Gene: SUDS3

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.84 0.60 0.712

The method score is based on:

Property Details
Experiments 12724404, 24981860, 35271311, 23752268, 26949739
Identification Methods affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006338 - chromatin remodeling
GO:0019899 - enzyme binding
and 7 others

more...
Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 488
Hs

1 328
+ Hs
+ Hs
+ Hs
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+ Hs
+ Mm
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024