HitPredict

Interactor 1: HDAC2 (Q92769)
Histone deacetylase 2 (HD2) (EC 3.5.1.98) (Protein deacylase HDAC2) (EC 3.5.1.-)
Gene: HDAC2

Interactor 2: HELLS (Q9NRZ9)
Lymphoid-specific helicase (EC 3.6.4.-) (Proliferation-associated SNF2-like protein) (SWI/SNF2-related matrix-associated actin-dependent regulator of chromatin subfamily A member 6)
Gene: HELLS

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	19561196, 30737378, 17967891
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003682 - chromatin binding GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 488 Hs			1 838
+	Hs
		1018617 HDAC2_HUMAN (1-488): 0: 707: 100.00		CHD3_HUMAN (50-828): 0: 649: 24.79
+	Hs
		847037 HDAC2_HUMAN (1-488): 0: 707: 100.00		SMCA4_HUMAN (9-838): 0: 633: 24.89
+	Mm
		936385 HDAC2_MOUSE (1-488): 0: 704: 99.39		SMCA4_MOUSE (9-838): 0: 636: 25.42
+	Hs
		1059770 HDAC2_HUMAN (1-488): 0: 707: 100.00		CHD4_HUMAN (51-828): 0: 630: 25.39
+	Mm
		936393 HDAC2_MOUSE (1-488): 0: 704: 99.39		Q5DTP7_MOUSE (51-828): 0: 631: 25.39
+	Hs
		1255037 HDAC2_HUMAN (1-488): 0: 707: 100.00		CHD5_HUMAN (50-835): 0: 627: 24.83
+	Mm
		56900 HDAC2_MOUSE (1-488): 0: 704: 99.39		CHD5_MOUSE (50-835): 0: 618: 25.17
+	Hs
		229453 HDAC2_HUMAN (1-488): 0: 707: 100.00		SMCA5_HUMAN (75-833): 0: 607: 30.76
+	Hs
		1018465 HDAC1_HUMAN (1-443): 0: 642: 90.07		CHD3_HUMAN (50-828): 0: 649: 24.79
+	Hs
		846833 HDAC2_HUMAN (1-488): 0: 707: 100.00		SMCA2_HUMAN (27-838): 0: 584: 26.37
+	Mm
		140261 HDAC1_MOUSE (1-443): 0: 645: 90.29		SMCA4_MOUSE (9-838): 0: 636: 25.42
+	Hs
		846962 HDAC1_HUMAN (1-443): 0: 642: 90.07		SMCA4_HUMAN (9-838): 0: 633: 24.89
+	Mm
		140286 HDAC1_MOUSE (1-443): 0: 645: 90.29		CHD4_MOUSE (51-828): 0: 629: 25.39
+	Hs
		1038382 HDAC1_HUMAN (1-443): 0: 642: 90.07		CHD4_HUMAN (51-828): 0: 630: 25.39
+	Hs
		1038563 HDAC1_HUMAN (1-443): 0: 642: 90.07		CHD5_HUMAN (50-835): 0: 627: 24.83
+	Mm
		56897 HDAC1_MOUSE (1-443): 0: 645: 90.29		CHD5_MOUSE (50-835): 0: 618: 25.17
+	Dm
		332806 HDAC1_DROME (5-472): 0: 653: 77.92		CHDM_DROME (41-829): 0: 596: 25.20
+	Dm
		1097627 HDAC1_DROME (5-472): 0: 653: 77.92		ISWI_DROME (101-833): 0: 584: 30.20
+	Hs
		846768 HDAC1_HUMAN (1-443): 0: 642: 90.07		SMCA2_HUMAN (27-838): 0: 584: 26.37
+	Hs
		1270443 HDAC2_HUMAN (1-488): 0: 707: 100.00		SMRCD_HUMAN (206-744): 1.53e-92: 315: 37.59