HitPredict

Interactor 1: HDAC2 (Q92769)
Histone deacetylase 2 (HD2) (EC 3.5.1.98) (Protein deacylase HDAC2) (EC 3.5.1.-)
Gene: HDAC2

Interactor 2: DNM3B (Q9UBC3)
DNA (cytosine-5)-methyltransferase 3B (Dnmt3b) (EC 2.1.1.37) (DNA methyltransferase HsaIIIB) (DNA MTase HsaIIIB) (M.HsaIIIB)
Gene: DNMT3B

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.624

Property	Details
Experiments	15120635, 23708667
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 488 Hs			1 853
+	Hs
		1038774 HDAC1_HUMAN (1-443): 0: 642: 90.07		DNM3B_HUMAN (1-853): 0: 1352: 100.00
+	Rn
		100231 F7ENH8_RAT (1-488): 0: 706: 98.98		Q1LZ51_RAT (1-853): 0: 1270: 82.16
+	Hs
		1038858 HDAC1_HUMAN (1-443): 0: 642: 90.07		DNM3A_HUMAN (30-852): 0: 1126: 49.82
+	Hs
		1038796 HDAC1_HUMAN (1-443): 0: 642: 90.07		DNM3L_HUMAN (417-758): 2.76e-164: 484: 36.81
+	Hs
		1038468 HDAC1_HUMAN (1-443): 0: 642: 90.07		PWP2B_HUMAN (15-310): 4.83e-94: 309: 25.32
+	Hs
		1270385 HDAC2_HUMAN (1-488): 0: 707: 100.00		PWP2A_HUMAN (45-310): 1.4e-63: 230: 19.50
+	Hs
		1038633 HDAC1_HUMAN (1-443): 0: 642: 90.07		PWP2A_HUMAN (45-310): 1.4e-63: 230: 19.50