Interactor 1: HDAC2 (Q92769)
Histone deacetylase 2 (HD2) (EC 3.5.1.98) (Protein deacylase HDAC2) (EC 3.5.1.-)
Gene: HDAC2

Interactor 2: RCOR1 (Q9UKL0)
REST corepressor 1 (Protein CoREST)
Gene: RCOR1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.980

The method score is based on:

Property Details
Experiments 12032298, 11171972, 24981860, 33961781, 34709266, 24239129, 12192000, 11102443, 30737378, 35271311, 21258344, 23752268, 26949739
Identification Methods biochemical, affinity chromatography technology, proximity labelling technology, cross-linking study, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains ELM2~Hist_deacetyl, Hist_deacetyl~Myb_DNA-binding
Common GO terms GO:0000118 - histone deacetylase complex
GO:0003682 - chromatin binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0019899 - enzyme binding
and 1 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 488
Hs

1 485
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Last updated: 15 Jul 2024