HitPredict

Interactor 1: HDAC2 (Q92769)
Histone deacetylase 2 (HD2) (EC 3.5.1.98) (Protein deacylase HDAC2) (EC 3.5.1.-)
Gene: HDAC2

Interactor 2: PKP3 (Q9Y446)
Plakophilin-3
Gene: PKP3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30737378
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0019899 - enzyme binding
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 488 Hs			1 797
+	Hs
		717252 HDAC2_HUMAN (1-488): 0: 707: 100.00		CTNB1_HUMAN (101-739): 1.82e-106: 346: 16.11
+	Hs
		542396 HDAC2_HUMAN (1-488): 0: 707: 100.00		PLAK_HUMAN (114-739): 1.02e-90: 303: 15.13
+	Hs
		717060 HDAC1_HUMAN (1-443): 0: 642: 90.07		CTNB1_HUMAN (101-739): 1.82e-106: 346: 16.11
+	Hs
		542310 HDAC1_HUMAN (1-443): 0: 642: 90.07		PLAK_HUMAN (114-739): 1.02e-90: 303: 15.13
+	Hs
		134940 HDAC2_HUMAN (1-488): 0: 707: 100.00		IMA3_HUMAN (25-485): 4.99e-56: 202: 10.87
+	Hs
		1354176 HDAC6_HUMAN (11-363): 6.94e-102: 332: 24.04		PKP3_HUMAN (1-797): 0: 569: 100.00
+	Hs
		131481 HDAC2_HUMAN (1-488): 0: 707: 100.00		IMA4_HUMAN (24-469): 1.87e-51: 190: 10.57
+	Hs
		134892 HDAC1_HUMAN (1-443): 0: 642: 90.07		IMA3_HUMAN (25-485): 4.99e-56: 202: 10.87
+	Hs
		131432 HDAC1_HUMAN (1-443): 0: 642: 90.07		IMA4_HUMAN (24-469): 1.87e-51: 190: 10.57
+	Hs
		239220 HDAC6_HUMAN (11-363): 6.94e-102: 332: 24.04		CTND1_HUMAN (24-794): 7.12e-130: 412: 24.50
+	Hs
		626124 HDAC1_HUMAN (1-443): 0: 642: 90.07		APC_HUMAN (329-537): 1.78e-09: 63.7: 23.85
+	Hs
		717395 HDAC6_HUMAN (11-363): 6.94e-102: 332: 24.04		CTNB1_HUMAN (101-739): 1.82e-106: 346: 16.11
+	Hs
		542470 HDAC6_HUMAN (11-363): 6.94e-102: 332: 24.04		PLAK_HUMAN (114-739): 1.02e-90: 303: 15.13
+	Mm
		192637 HDAC4_MOUSE (1-377): 6.12e-133: 412: 23.89		IMA4_MOUSE (24-469): 5.66e-52: 191: 10.57
+	Mm
		1157718 HDAC4_MOUSE (1-377): 6.12e-133: 412: 23.89		Q8BNP7_MOUSE (199-689): 2.5e-11: 69.7: 15.34
+	Mm
		1142527 HDAC4_MOUSE (1-377): 6.12e-133: 412: 23.89		APC_MOUSE (329-537): 1.3e-09: 64.4: 23.85
+	Hs
		717231 HDAC7_HUMAN (29-280): 1.96e-23: 106: 26.37		CTNB1_HUMAN (101-739): 1.82e-106: 346: 16.11