HitPredict

Interactor 1: STAM1 (Q92783)
Signal transducing adapter molecule 1 (STAM-1)
Gene: STAM

Interactor 2: ITCH (Q96J02)
E3 ubiquitin-protein ligase Itchy homolog (Itch) (EC 2.3.2.26) (Atrophin-1-interacting protein 4) (AIP4) (HECT-type E3 ubiquitin transferase Itchy homolog) (NFE2-associated polypeptide 1) (NAPP1)
Gene: ITCH

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.64 0.60 0.624

The method score is based on:

Property Details
Experiments 22275353, 26508657
Identification Methods pull down, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005829 - cytosol
GO:0031901 - early endosome membrane
GO:0043231 - intracellular membrane-bounded organelle
GO:0044389 - ubiquitin-like protein ligase binding
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 540
Hs

1 903
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024