Interactor 1: CBP (Q92793)
CREB-binding protein (Histone lysine acetyltransferase CREBBP) (EC 2.3.1.48) (Protein lactyltransferas CREBBP) (EC 2.3.1.-) (Protein-lysine acetyltransferase CREBBP) (EC 2.3.1.-)
Gene: CREBBP

Interactor 2: CBP (Q92793)
CREB-binding protein (Histone lysine acetyltransferase CREBBP) (EC 2.3.1.48) (Protein lactyltransferas CREBBP) (EC 2.3.1.-) (Protein-lysine acetyltransferase CREBBP) (EC 2.3.1.-)
Gene: CREBBP

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.78 1.00 0.888

The method score is based on:

Property Details
Experiments 19805293, 28630323, 30893604, 11046145
Identification Methods enzymatic study
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Bromodomain~Bromodomain, Bromodomain~RING_CBP-p300, HAT_KAT11~HAT_KAT11, ZZ~ZZ
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000123 - histone acetyltransferase complex
GO:0000785 - chromatin
GO:0001223 - transcription coactivator binding
GO:0001666 - response to hypoxia
and 44 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

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Hs

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Last updated: 15 Jul 2024