HitPredict

Interactor 1: CBP (Q92793)
CREB-binding protein (Histone lysine acetyltransferase CREBBP) (EC 2.3.1.48) (Protein lactyltransferas CREBBP) (EC 2.3.1.-) (Protein-lysine acetyltransferase CREBBP) (EC 2.3.1.-)
Gene: CREBBP

Interactor 2: KLF15 (Q9UIH9)
Krueppel-like factor 15 (Kidney-enriched krueppel-like factor)
Gene: KLF15

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.621

Property	Details
Experiments	35140242, 35016035
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2442 Hs			1 416
+	Hs
		1046727 CBP_HUMAN (1-2442): 0: 1104: 100.00		KLF5_HUMAN (312-404): 4.14e-34: 134: 64.52
+	Hs
		970933 CBP_HUMAN (1-2442): 0: 1104: 100.00		SP3_HUMAN (319-415): 2.25e-30: 125: 57.73
+	Hs
		1032219 CBP_HUMAN (1-2442): 0: 1104: 100.00		KLF1_HUMAN (321-403): 8.19e-31: 123: 67.47
+	Hs
		316951 CBP_HUMAN (1-2442): 0: 1104: 100.00		KLF8_HUMAN (319-403): 5.41e-31: 123: 63.53
+	Hs
		435150 CBP_HUMAN (1-2442): 0: 1104: 100.00		SP1_HUMAN (319-404): 4.98e-29: 121: 63.95
+	Hs
		1270843 CBP_HUMAN (1-2442): 0: 1104: 100.00		KLF13_HUMAN (294-403): 5.87e-29: 116: 53.57
+	Hs
		998688 EP300_HUMAN (1-2426): 0: 874: 55.06		KLF5_HUMAN (312-404): 4.14e-34: 134: 64.52
+	Hs
		970912 EP300_HUMAN (1-2426): 0: 874: 55.06		SP3_HUMAN (319-415): 2.25e-30: 125: 57.73
+	Hs
		157893 EP300_HUMAN (1-2426): 0: 874: 55.06		KLF11_HUMAN (295-403): 3.78e-30: 123: 55.05
+	Hs
		316867 EP300_HUMAN (1-2426): 0: 874: 55.06		KLF8_HUMAN (319-403): 5.41e-31: 123: 63.53
+	Hs
		998655 EP300_HUMAN (1-2426): 0: 874: 55.06		KLF1_HUMAN (321-403): 8.19e-31: 123: 67.47
+	Hs
		435071 EP300_HUMAN (1-2426): 0: 874: 55.06		SP1_HUMAN (319-404): 4.98e-29: 121: 63.95
+	Hs
		999055 EP300_HUMAN (1-2426): 0: 874: 55.06		KLF16_HUMAN (319-403): 9.02e-31: 120: 62.35
+	Hs
		884141 EP300_HUMAN (1-2426): 0: 874: 55.06		KLF3_HUMAN (319-403): 1.71e-29: 119: 63.53
+	Hs
		999239 EP300_HUMAN (1-2426): 0: 874: 55.06		KLF13_HUMAN (294-403): 5.87e-29: 116: 53.57
+	Hs
		999184 EP300_HUMAN (1-2426): 0: 874: 55.06		KLF15_HUMAN (349-414): 7.07e-21: 95.9: 36.77
+	Hs
		170186 TIF1A_HUMAN (667-1202): 2.17e-34: 147: 17.97		ZN254_HUMAN (108-316): 1.43e-50: 182: 6.64
+	Hs
		317033 TRI33_HUMAN (694-1207): 3.25e-37: 156: 14.83		KLF8_HUMAN (319-403): 5.41e-31: 123: 63.53
+	Hs
		64157 TIF1A_HUMAN (667-1202): 2.17e-34: 147: 17.97		ZN726_HUMAN (91-260): 2.2e-29: 122: 6.82
+	Hs
		1158957 TRI33_HUMAN (694-1207): 3.25e-37: 156: 14.83		ZFP1_HUMAN (290-414): 8.33e-14: 74.3: 16.00