HitPredict

Interactor 1: CBP (Q92793)
CREB-binding protein (Histone lysine acetyltransferase CREBBP) (EC 2.3.1.48) (Protein lactyltransferas CREBBP) (EC 2.3.1.-) (Protein-lysine acetyltransferase CREBBP) (EC 2.3.1.-)
Gene: CREBBP

Interactor 2: ZHX1 (Q9UKY1)
Zinc fingers and homeoboxes protein 1
Gene: ZHX1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	28680062
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000785 - chromatin GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2442 Hs			1 873
+	Hs
		1270817 CBP_HUMAN (1-2442): 0: 1104: 100.00		DUX4_HUMAN (450-672): 2.35e-32: 132: 15.86
+	Hs
		641506 CBP_HUMAN (1-2442): 0: 1104: 100.00		PAX6_HUMAN (628-784): 3.52e-12: 71.3: 18.29
+	Hs
		741073 CBP_HUMAN (1-2442): 0: 1104: 100.00		ZEB1_HUMAN (18-179): 9.39e-10: 64.8: 18.52
+	Hs
		999170 EP300_HUMAN (1-2426): 0: 874: 55.06		DUX4_HUMAN (450-672): 2.35e-32: 132: 15.86
+	Hs
		641388 EP300_HUMAN (1-2426): 0: 874: 55.06		PAX6_HUMAN (628-784): 3.52e-12: 71.3: 18.29
+	Hs
		741038 EP300_HUMAN (1-2426): 0: 874: 55.06		ZEB1_HUMAN (18-179): 9.39e-10: 64.8: 18.52
+	Hs
		231231 EP300_HUMAN (1-2426): 0: 874: 55.06		ZEB2_HUMAN (63-259): 2.75e-09: 63.2: 15.15
+	Hs
		1067137 BRD3_HUMAN (1073-1195): 1.36e-33: 143: 30.89		ZHX3_HUMAN (1-873): 0: 589: 32.70
+	Hs
		1199921 PHIP_HUMAN (1045-1205): 3.22e-45: 183: 30.36		ZFHX4_HUMAN (198-722): 3.99e-27: 121: 12.55
+	Hs
		1080554 PHIP_HUMAN (1045-1205): 3.22e-45: 183: 30.36		ZFHX3_HUMAN (295-729): 4.4e-11: 69.4: 13.15
+	Hs
		1357652 TRI33_HUMAN (694-1207): 3.25e-37: 156: 14.83		LHX6_HUMAN (452-558): 2.69e-14: 77.4: 17.76
+	Ce
		1353451 Q9TZB8_CAEEL (353-449): 8.03e-43: 160: 43.40		V6CLN5_CAEEL (195-634): 4.57e-10: 65.9: 11.11
+	Hs
		170297 TIF1A_HUMAN (667-1202): 2.17e-34: 147: 17.97		LHX1_HUMAN (332-565): 7.88e-13: 73.2: 17.92
+	Hs
		170262 TIF1A_HUMAN (667-1202): 2.17e-34: 147: 17.97		PAX6_HUMAN (628-784): 3.52e-12: 71.3: 18.29
+	Hs
		1199217 PB1_HUMAN (1040-1275): 1.29e-12: 76: 14.83		LHX6_HUMAN (452-558): 2.69e-14: 77.4: 17.76
+	Hs
		63970 BPTF_HUMAN (1831-2314): 7.5e-12: 73.6: 11.09		DUXA_HUMAN (435-549): 7.66e-16: 79: 13.91
+	Hs
		822645 PB1_HUMAN (1040-1275): 1.29e-12: 76: 14.83		LHX1_HUMAN (332-565): 7.88e-13: 73.2: 17.92
+	Hs
		641466 PB1_HUMAN (1040-1275): 1.29e-12: 76: 14.83		PAX6_HUMAN (628-784): 3.52e-12: 71.3: 18.29
+	Hs
		641391 BPTF_HUMAN (1831-2314): 7.5e-12: 73.6: 11.09		PAX6_HUMAN (628-784): 3.52e-12: 71.3: 18.29
+	Hs
		203210 SYNJ1_HUMAN (1984-2407): 1.04e-11: 73.3: 10.86		PAX6_HUMAN (628-784): 3.52e-12: 71.3: 18.29