HitPredict

Interactor 1: KAT2A (Q92830)
Histone acetyltransferase KAT2A (EC 2.3.1.48) (General control of amino acid synthesis protein 5-like 2) (Histone acetyltransferase GCN5) (hGCN5) (Histone glutaryltransferase KAT2A) (EC 2.3.1.-) (Histone succinyltransferase KAT2A) (EC 2.3.1.-) (Lysine acetyltransferase 2A) (STAF97)
Gene: KAT2A

Interactor 2: KAT2B (Q92831)
Histone acetyltransferase KAT2B (EC 2.3.1.48) (Histone acetyltransferase PCAF) (Histone acetylase PCAF) (Lysine acetyltransferase 2B) (P300/CBP-associated factor) (P/CAF) (Spermidine acetyltransferase KAT2B) (EC 2.3.1.57)
Gene: KAT2B

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.54 1.00 0.737

The method score is based on:

Property Details
Experiments 24981860, 10373431
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Acetyltransf_1~Acetyltransf_1, Bromodomain~Bromodomain, PCAF_N~PCAF_N
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000124 - SAGA complex
GO:0003682 - chromatin binding
GO:0003713 - transcription coactivator activity
GO:0004402 - histone acetyltransferase activity
and 27 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 837
Hs

1 832
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Last updated: 15 Jul 2024