HitPredict

Interactor 1: KAT2A (Q92830)
Histone acetyltransferase KAT2A (EC 2.3.1.48) (General control of amino acid synthesis protein 5-like 2) (Histone acetyltransferase GCN5) (hGCN5) (Histone glutaryltransferase KAT2A) (EC 2.3.1.-) (Histone succinyltransferase KAT2A) (EC 2.3.1.-) (Lysine acetyltransferase 2A) (STAF97)
Gene: KAT2A

Interactor 2: CSR2B (Q9H8E8)
Cysteine-rich protein 2-binding protein (CSRP2-binding protein) (ADA2A-containing complex subunit 2) (ATAC2) (CRP2-binding partner) (CRP2BP) (Lysine acetyltransferase 14)
Gene: KAT14

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.87	1.00	0.935

The method score is based on:

Property	Details
Experiments	33961781, 18838386, 31753913, 24981860, 37682711, 20562830
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type	physical association, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	Acetyltransf_1~Acetyltransf_1
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0004402 - histone acetyltransferase activity GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm and 8 others more... GO:0006355 - regulation of DNA-templated transcription GO:0006357 - regulation of transcription by RNA polymerase II GO:0045995 - regulation of embryonic development GO:0051302 - regulation of cell division GO:0051726 - regulation of cell cycle GO:0072686 - mitotic spindle GO:0090043 - regulation of tubulin deacetylation GO:0140672 - ATAC complex
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1	837
Hs

1	782

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024