HitPredict

Interactor 1: KAT2B (Q92831)
Histone acetyltransferase KAT2B (EC 2.3.1.48) (Histone acetyltransferase PCAF) (Histone acetylase PCAF) (Lysine acetyltransferase 2B) (P300/CBP-associated factor) (P/CAF) (Spermidine acetyltransferase KAT2B) (EC 2.3.1.57)
Gene: KAT2B

Interactor 2: MED23 (Q9ULK4)
Mediator of RNA polymerase II transcription subunit 23 (Activator-recruited cofactor 130 kDa component) (ARC130) (Cofactor required for Sp1 transcriptional activation subunit 3) (CRSP complex subunit 3) (Mediator complex subunit 23) (Protein sur-2 homolog) (hSur-2) (Transcriptional coactivator CRSP130) (Vitamin D3 receptor-interacting protein complex 130 kDa component) (DRIP130)
Gene: MED23

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	25281560
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003713 - transcription coactivator activity GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006355 - regulation of DNA-templated transcription GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 832 Hs			1 1368
+	Hs
		1271465 KAT2A_HUMAN (63-832): 0: 1056: 73.42		MED23_HUMAN (1-1368): 0: 2164: 100.00
+	Mm
		1194507 KAT2A_MOUSE (67-832): 0: 1044: 74.19		MED23_MOUSE (1-1368): 0: 2083: 96.27
+	Hs
		1067187 BRD3_HUMAN (672-830): 6.16e-33: 138: 22.67		MED23_HUMAN (1-1368): 0: 2164: 100.00
+	Hs
		245084 BRD4_HUMAN (680-832): 1.99e-31: 134: 22.15		MED23_HUMAN (1-1368): 0: 2164: 100.00