HitPredict

Interactor 1: EDA (Q92838)
Ectodysplasin-A (Ectodermal dysplasia protein) (EDA protein) [Cleaved into: Ectodysplasin-A, membrane form; Ectodysplasin-A, secreted form]
Gene: EDA

Interactor 2: EDA (Q92838)
Ectodysplasin-A (Ectodermal dysplasia protein) (EDA protein) [Cleaved into: Ectodysplasin-A, membrane form; Ectodysplasin-A, secreted form]
Gene: EDA

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.647

The method score is based on:

Property Details
Experiments 14656435
Identification Methods x-ray crystallography
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains TNF~TNF
Common GO terms GO:0005102 - signaling receptor binding
GO:0005123 - death receptor binding
GO:0005164 - tumor necrosis factor receptor binding
GO:0005581 - collagen trimer
GO:0005615 - extracellular space
and 26 others

more...
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 391
Hs

1 391
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024