Interactor 1: TANK (Q92844)
TRAF family member-associated NF-kappa-B activator (TRAF-interacting protein) (I-TRAF)
Gene: TANK
Interactor 2: TBK1 (Q9UHD2)
Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (NF-kappa-B-activating kinase) (T2K) (TANK-binding kinase 1)
Gene: TBK1
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.98 | 0.60 | 0.767 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 25409927, 30561431, 33961781, 10581243, 17823124, 35289316, 21903422, 23007157, 17568778, 21988832, 27035970, 24488098, 14743216, 30420664, 29395067, 31114588, 32707033, 36736316, 23286385, 17468758 and 6 others
more... |
| Identification Methods | affinity chromatography technology, two hybrid, proximity labelling technology, tandem affinity purification, anti tag coimmunoprecipitation, pull down, anti bait coimmunoprecipitation, virotrap, luminescence based mammalian interactome mapping |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0007249 - canonical NF-kappaB signal transduction GO:0032481 - positive regulation of type I interferon production GO:0051607 - defense response to virus and 2 others more... |
| Homologous interactions | 5 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
