Interactor 1: TANK (Q92844)
TRAF family member-associated NF-kappa-B activator (TRAF-interacting protein) (I-TRAF)
Gene: TANK

Interactor 2: NEMO (Q9Y6K9)
NF-kappa-B essential modulator (NEMO) (FIP-3) (IkB kinase-associated protein 1) (IKKAP1) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (I-kappa-B kinase subunit gamma) (IKK-gamma) (IKKG) (IkB kinase subunit gamma) (NF-kappa-B essential modifier)
Gene: IKBKG

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 0.60 0.757

The method score is based on:

Property Details
Experiments 25861989, 30561431, 12133833, 35289316, 20484576, 28514442, 33961781, 17468758, 21988832, 21419663
Identification Methods affinity chromatography technology, two hybrid, pull down, anti tag coimmunoprecipitation, virotrap
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006974 - DNA damage response
GO:0007249 - canonical NF-kappaB signal transduction
GO:0031625 - ubiquitin protein ligase binding
and 2 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 425
Hs

1 419
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024