Interactor 1: RAD50 (Q92878)
DNA repair protein RAD50 (hRAD50) (EC 3.6.-.-)
Gene: RAD50

Interactor 2: RAD50 (Q92878)
DNA repair protein RAD50 (hRAD50) (EC 3.6.-.-)
Gene: RAD50

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.67 1.00 0.820

The method score is based on:

Property Details
Experiments 28134932, 22833675
Identification Methods x-ray crystallography, affinity chromatography technology, x ray scattering, fluorescent resonance energy transfer, cross-linking study
Interaction Type association, physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains AAA_23~AAA_23, AAA_23~SbcC_Walker_B, Rad50_zn_hook~Rad50_zn_hook, SbcC_Walker_B~SbcC_Walker_B
Common GO terms GO:0000019 - regulation of mitotic recombination
GO:0000723 - telomere maintenance
GO:0000722 - telomere maintenance via recombination
GO:0000724 - double-strand break repair via homologous recombination
GO:0000729 - DNA double-strand break processing
and 35 others

more...

Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 1312
Hs

1 1312
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Last updated: 15 Jul 2024