HitPredict

Interactor 1: XPF (Q92889)
DNA repair endonuclease XPF (EC 3.1.-.-) (DNA excision repair protein ERCC-4) (DNA repair protein complementing XP-F cells) (Xeroderma pigmentosum group F-complementing protein)
Gene: ERCC4

Interactor 2: MUS81 (Q96NY9)
Crossover junction endonuclease MUS81 (EC 3.1.22.-)
Gene: MUS81

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.65 1.00 0.811

The method score is based on:

Property Details
Experiments 28514442, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains ERCC4~ERCC4
Common GO terms GO:0000712 - resolution of meiotic recombination intermediates
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006281 - DNA repair
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 916
Hs

1 551
+ Pf

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024