HitPredict

Interactor 1: RENT1 (Q92900)
Regulator of nonsense transcripts 1 (EC 3.6.4.12) (EC 3.6.4.13) (ATP-dependent helicase RENT1) (Nonsense mRNA reducing factor 1) (NORF1) (Up-frameshift suppressor 1 homolog) (hUpf1)
Gene: UPF1

Interactor 2: RENT1 (Q92900)
Regulator of nonsense transcripts 1 (EC 3.6.4.12) (EC 3.6.4.13) (ATP-dependent helicase RENT1) (Nonsense mRNA reducing factor 1) (NORF1) (Up-frameshift suppressor 1 homolog) (hUpf1)
Gene: UPF1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.33 1.00 0.575

The method score is based on:

Property Details
Experiments 12417715
Identification Methods anti tag coimmunoprecipitation
Interaction Type association

The annotation score is based on:

Property Details
Interacting Pfam domains AAA_11~AAA_11, AAA_11~AAA_12, AAA_11~UPF1_1B_dom, AAA_12~AAA_12, AAA_12~ResIII, AAA_12~UPF1_1B_dom, AAA_12~UPF1_Zn_bind, ResIII~ResIII, ResIII~UPF1_1B_dom, UPF1_Zn_bind~UPF1_Zn_bind
Common GO terms GO:0000184 - nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0000781 - chromosome, telomeric region
GO:0000785 - chromatin
GO:0000932 - P-body
GO:0000956 - nuclear-transcribed mRNA catabolic process
and 31 others

more...
Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 1129
Hs

1 1129
+ Sc
+ Hs
+ Hs
+ Dm
+ Hs
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024