Interactor 1: RENT1 (Q92900)
Regulator of nonsense transcripts 1 (EC 3.6.4.12) (EC 3.6.4.13) (ATP-dependent helicase RENT1) (Nonsense mRNA reducing factor 1) (NORF1) (Up-frameshift suppressor 1 homolog) (hUpf1)
Gene: UPF1
Interactor 2: RENT2 (Q9HAU5)
Regulator of nonsense transcripts 2 (Up-frameshift suppressor 2 homolog) (hUpf2)
Gene: UPF2
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.98 | 1.00 | 0.991 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 11544179, 11163187, 16488880, 16452507, 14527413, 12723973, 11073994, 35271311, 37071682, 16086026, 19417104, 21145460, 18256688, 20371770, 24778252, 18066079, 19503078, 19478851, 19556969, 17469741 and 3 others
more... |
| Identification Methods | affinity chromatography technology, cross-linking study, pull down, atpase assay, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, nuclear magnetic resonance, two hybrid, x-ray crystallography |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | UPF1_Zn_bind~Upf2 |
| Common GO terms | GO:0000184 - nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol and 4 others more... |
| Homologous interactions | 2 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
