HitPredict

Interactor 1: RENT1 (Q92900)
Regulator of nonsense transcripts 1 (EC 3.6.4.12) (EC 3.6.4.13) (ATP-dependent helicase RENT1) (Nonsense mRNA reducing factor 1) (NORF1) (Up-frameshift suppressor 1 homolog) (hUpf1)
Gene: UPF1

Interactor 2: MOV10 (Q9HCE1)
Helicase MOV-10 (EC 3.6.4.13) (Armitage homolog) (Moloney leukemia virus 10 protein)
Gene: MOV10

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.80 1.00 0.895

The method score is based on:

Property Details
Experiments 29395067, 24778252, 35271311, 34517762
Identification Methods proximity labelling technology, affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains AAA_11~AAA_11, AAA_11~AAA_12, AAA_12~AAA_12, AAA_12~ResIII, AAA_11~UPF1_1B_dom, AAA_12~UPF1_1B_dom, AAA_12~UPF1_Zn_bind
Common GO terms GO:0000932 - P-body
GO:0003723 - RNA binding
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005829 - cytosol
and 3 others

more...
Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 1129
Hs

1 1003
+ Hs
+ Hs
+ Dm
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+ Dm
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024