HitPredict

Interactor 1: IPO5 (O00410)
Importin-5 (Imp5) (Importin subunit beta-3) (Karyopherin beta-3) (Ran-binding protein 5) (RanBP5)
Gene: IPO5

Interactor 2: RAN (P62826)
GTP-binding nuclear protein Ran (EC 3.6.5.-) (Androgen receptor-associated protein 24) (GTPase Ran) (Ras-like protein TC4) (Ras-related nuclear protein)
Gene: RAN

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.79 1.00 0.893

The method score is based on:

Property Details
Experiments 9114010, 35271311, 27114554, 10944119
Identification Methods pull down, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Importin_rep_4~Ras
Common GO terms GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005643 - nuclear pore
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus
and 5 others

more...
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 1097
Hs

1 216
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024