Interactor 1: HPS1 (Q92902)
BLOC-3 complex member HPS1 (Hermansky-Pudlak syndrome 1 protein)
Gene: HPS1

Interactor 2: HPS4 (Q9NQG7)
BLOC-3 complex member HPS4 (Hermansky-Pudlak syndrome 4 protein) (Light-ear protein homolog)
Gene: HPS4

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.49 1.00 0.705

The method score is based on:

Property Details
Experiments 12756248
Identification Methods anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, molecular sieving, cosedimentation through density gradient
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Fuz_longin_1~Intu_longin_1
Common GO terms GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005737 - cytoplasm
GO:0005764 - lysosome
GO:0005829 - cytosol
GO:0007040 - lysosome organization
and 7 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 700
Hs

1 708
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024