HitPredict

Interactor 1: CSN5 (Q92905)
COP9 signalosome complex subunit 5 (SGN5) (Signalosome subunit 5) (EC 3.4.-.-) (Jun activation domain-binding protein 1)
Gene: COPS5

Interactor 2: KLH15 (Q96M94)
Kelch-like protein 15
Gene: KLHL15

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.621

Property	Details
Experiments	19615732, 21145461
Identification Methods	affinity chromatography technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 334 Hs			1 604
+	Hs
		1121249 CSN5_HUMAN (1-334): 6.64e-131: 378: 100.00		KLH22_HUMAN (8-602): 0: 540: 29.56
+	Hs
		1233686 CSN5_HUMAN (1-334): 6.64e-131: 378: 100.00		KLH36_HUMAN (2-591): 4.28e-147: 440: 26.25
+	Hs
		1153787 CSN5_HUMAN (1-334): 6.64e-131: 378: 100.00		KLH10_HUMAN (19-592): 1.16e-142: 428: 22.76
+	Hs
		1272661 CSN5_HUMAN (1-334): 6.64e-131: 378: 100.00		KLHL8_HUMAN (4-590): 2.29e-140: 423: 22.26
+	Hs
		1121485 CSN5_HUMAN (1-334): 6.64e-131: 378: 100.00		KLH26_HUMAN (8-596): 3.6e-137: 414: 29.53
+	Hs
		1164621 CSN5_HUMAN (1-334): 6.64e-131: 378: 100.00		KLH24_HUMAN (4-591): 7.18e-134: 405: 20.88
+	Hs
		1272662 CSN5_HUMAN (1-334): 6.64e-131: 378: 100.00		KLHL9_HUMAN (102-476): 2.26e-36: 146: 12.28
+	Hs
		1272664 CSN5_HUMAN (1-334): 6.64e-131: 378: 100.00		KLH13_HUMAN (132-476): 1.01e-34: 141: 11.36
+	Hs
		1120793 CSN5_HUMAN (1-334): 6.64e-131: 378: 100.00		KLH12_HUMAN (410-600): 1.34e-22: 103: 20.00
+	Hs
		299528 CSN5_HUMAN (1-334): 6.64e-131: 378: 100.00		KLH18_HUMAN (238-377): 2.48e-10: 65.3: 15.00
+	Hs
		131121 PSDE_HUMAN (50-331): 1.67e-79: 246: 31.51		IPP_HUMAN (489-597): 1.1e-16: 85.3: 27.27