Interactor 1: DET1 (Q7L5Y6)
DET1 homolog (De-etiolated-1 homolog)
Gene: DET1
Interactor 2: COP1 (Q8NHY2)
E3 ubiquitin-protein ligase COP1 (EC 2.3.2.27) (Constitutive photomorphogenesis protein 1 homolog) (hCOP1) (RING finger and WD repeat domain protein 2) (RING finger protein 200) (RING-type E3 ubiquitin transferase RFWD2)
Gene: COP1
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.95 | 0.55 | 0.725 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 17452440, 28514442, 14739464, 30692133, 31155351, 33961781, 32041890, 33911083, 17968316, 37390815, 21572435, 25117710 |
| Identification Methods | affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0016567 - protein ubiquitination GO:0031464 - Cul4A-RING E3 ubiquitin ligase complex GO:0032436 - positive regulation of proteasomal ubiquitin-dependent protein catabolic process |
| Homologous interactions | 0 |
Service provided by Combinatics, Japan
Last updated: 11Aug2025
