HitPredict

Interactor 1: CSN5 (Q92905)
COP9 signalosome complex subunit 5 (SGN5) (Signalosome subunit 5) (EC 3.4.-.-) (Jun activation domain-binding protein 1)
Gene: COPS5

Interactor 2: PSD13 (Q9UNM6)
26S proteasome non-ATPase regulatory subunit 13 (26S proteasome regulatory subunit RPN9) (26S proteasome regulatory subunit S11) (26S proteasome regulatory subunit p40.5)
Gene: PSMD13

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31950832
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	JAB~PCI
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 334 Hs			1 376
+	Hs
		131110 PSDE_HUMAN (50-331): 1.67e-79: 246: 31.51		PSD13_HUMAN (1-376): 5.33e-175: 493: 100.00
+	Hs
		131124 PSDE_HUMAN (50-331): 1.67e-79: 246: 31.51		Q9Y6E3_HUMAN (1-376): 1.45e-167: 474: 96.82
+	Hs
		849285 PSMD7_HUMAN (52-325): 1.07e-66: 214: 14.79		PSD13_HUMAN (1-376): 5.33e-175: 493: 100.00
+	Hs
		849293 PSMD7_HUMAN (52-325): 1.07e-66: 214: 14.79		Q9Y6E3_HUMAN (1-376): 1.45e-167: 474: 96.82
+	Dm
		1180994 PSDE_DROME (41-331): 6.31e-82: 252: 31.35		Q7KMP8_DROME (3-376): 1.66e-142: 411: 44.95
+	Ce
		284027 PSDE_CAEEL (50-334): 3.9e-74: 232: 28.81		Q22253_CAEEL (6-376): 9.33e-136: 394: 40.16
+	Dm
		640774 PSMD7_DROME (51-325): 7.93e-65: 210: 15.04		Q7KMP8_DROME (3-376): 1.66e-142: 411: 44.95
+	Ce
		247773 O61792_CAEEL (51-323): 3.34e-60: 198: 15.49		Q22253_CAEEL (6-376): 9.33e-136: 394: 40.16
+	Sp
		784777 RPN11_SCHPO (45-331): 1.44e-74: 233: 28.91		RPN9_SCHPO (3-368): 6.9e-122: 359: 34.95
+	Sc
		797570 RPN11_YEAST (39-333): 9.57e-75: 234: 29.14		RPN9_YEAST (14-374): 3.08e-110: 329: 30.69
+	Mm
		193524 CSN5_MOUSE (1-334): 1.02e-130: 378: 99.40		CSN7B_MOUSE (199-373): 4.96e-46: 160: 18.18
+	Hs
		1272616 CSN5_HUMAN (1-334): 6.64e-131: 378: 100.00		CSN7B_HUMAN (199-373): 8.34e-46: 159: 17.61
+	Hs
		1272670 CSN5_HUMAN (1-334): 6.64e-131: 378: 100.00		CSN7A_HUMAN (188-373): 1.91e-43: 153: 21.93
+	Dm
		1359992 CSN5_DROME (6-333): 8.85e-129: 372: 74.70		CSN7_DROME (199-371): 3.88e-43: 152: 17.14
+	At
		1227262 CSN5A_ARATH (1-334): 5.43e-121: 354: 65.69		CSN7_ARATH (200-371): 7.87e-47: 162: 19.54
+	At
		1278363 CSN5B_ARATH (1-334): 8.46e-119: 348: 66.57		CSN7_ARATH (200-371): 7.87e-47: 162: 19.54
+	Ce
		954221 CSN5_CAEEL (5-329): 4.44e-108: 321: 56.88		EIF3M_CAEEL (198-374): 1.07e-39: 146: 21.67
+	An
		961359 CSN5_EMENI (8-332): 5.21e-105: 312: 54.10		CSN7_EMENI (177-374): 2.3e-38: 141: 19.90
+	Hs
		177046 EIF3H_HUMAN (52-320): 2.17e-66: 214: 18.57		EIF3M_HUMAN (180-367): 2.2e-47: 166: 20.31
+	Hs
		124889 EIF3F_HUMAN (44-328): 3.25e-64: 208: 14.48		EIF3M_HUMAN (180-367): 2.2e-47: 166: 20.31